CAS 11041-12-6 Pharmaceutical Grade Cholestyramine Powder Ch

Brand Name: SGONEK

Price: $100 -$120/Kilogram

Place of Origin: Shaanxi, China

Certification: ISO FDA SG COA MSDS

Grade: Food Grade, Medicine Grade

Payment Terms: T/T, Western Union, MoneyGram

Product Name:  Cholestyramine Cas No.:  11041-12-6
Molecular Formula:  C27H47N Purity:  99%min
Brand Name:  SGONEK Certification:  ISO FDA SG COA MSDS

CAS 11041-12-6 Pharmaceutical Grade Cholestyramine Powder Ch


Product Name : Cholestyramine   
CAS : 11041-12-6 
EINECS: 234-270-8 

Molecular Formula : C27H47N

 

Cholestyramine or colestyramine (Questran, Questran Light, Cholybar, Olestyr) is a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption. It is a strong ion exchange resin, which means it can exchange its chloride anions with anionic bile acids in the gastrointestinal tract and bind them strongly in the resin matrix. The functional group of the anion exchange resin is a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer. 

TEST

SPECIFICATIONS

RESULTS

Characteristics

White or off-white crystalline powder,odorless or 

some amine smell;Moisture absorption

white powder,some

 amine smell; moisture

 absorption

Identification

IR absorption spectrogram comply with

 reference atandard spectrogram

Conforms

Acidity

PH4.0~6.0

5.1

Dialysis quatemary Ammonnium

Conforms

Conforms

Chloride

13.0-17.0%(On drying basis)

16.2%

Loss on dryng

12.0% max

6.8%

Residue on ignition

0.1%max

Conforms

Heavy Metals

20ppm max

Conforms

Total plate count

1000/g max

Less than 10/g

Yeast and mold

100/g max

50/g

E.Coil.:

Negative

Negative

Active Acarus

Negative

Negative

Exchange capacity

Exchange sodium taurocholate per gram 

should be 2.0~2.2g on drying basis

2.1g

Conclusion

The results conform to USP standard


Cholestyramine removes bile acids from the body by forming insoluble complexes with bile acids in the intestine, which are then excreted in the feces. As a result of this loss of bile acids, more plasma cholesterol is converted to bile acids in the liver to normalize levels. This conversion of cholesterol into bile acids lowers plasma cholesterol levels.  
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